My dad was diagnosed with early on-set at 62. Was fortunate enough to get into an experimental program at Mayo in Rochester which seemed to stem the tide for awhile. My parents would drive 7 1/2 hours back and forth to Rochester every 6 weeks. It was pretty apparent he was getting the drug and not a placebo and at the end of the trial they said the results were not good enough for the drug to go forward. He was in the trial for a couple years until he had some brain swelling(which was a possible side effect) and they had to stop the treatments. I could tell when he had recently had his injection so to me it seemed as though the drug had some positive benefits in at least slowing down the progression. He would get an injection on one trip and the next trip would be the follow up and examination(MRI's, cognition tests, etc.). I could see a difference in his communication skills and a difference when he was 3-4 weeks since an injection and when he had been 9-10 weeks since his injection. After he was off the trial drug it was frustrating to watch the slow diminishing of communication and motor skills speed up. It is brutal on families...thank God my mom was a nurse and an amazing human being which helped alleviate a lot of the financial and emotional strain of having to go into a home and we were able to keep him at home. At the end he went down hill really fast and he passed away a little over 2 years ago now(at 74). He had pulled me aside a few years back and had also mentioned 20-25 years ago when my grandmother was in a home that under no circumstances did he ever want to go into a nursing home so when we had to check him into the hospital for pneumonia which eventually led to infections and aspiration pneumonia I had a feeling he would get his wish. I don't wish Alzheimers on anyone and they really need to find a cure.
My grandpa on my dads side had Alzheimer’s and it was brutal. Now my grandma has it. Great grandma on my moms had dementia but it didn’t come into play until around the time she turned 90 (lived to be 94) My grandpa on my moms side died due to brain cancer I’m screwed
Pretty jealous of Tom Mangelsen’s life. Photographing grizzlies in Jackson and kicking it with GOAT human Jane Goodall. What a way to do it.
That Danish zookeeper looks and sounds like a Bond villian. And regardless of his reasoning, fuck him.
The story on the NYC subway/renovation plan was interesting....crazy to think about how old some of that technology is.
Tim Green piece was really sad. I remember him from the #Atlanta Falcons when I was a kid and one of his first books Ruffians was a favorite of mine in my teenage years. ALS is fucking terrifying
I have read a decent bit about it and I think they make the truce between environmentalists, ranchers, and hunters (who imo should have no voice) out to be better than it is. There is a lot of mistrust, and wolves, particularly older / sick wolves still take cows. Giving ranchers the right to kill those wolves was basically the bare minimum to avoid them taking matters into their own hands. It’s clear that with the population as it is, that population mamangement and allowing ranchers some flexibility to protect their livelihood is a necessary compromise, but also that their reintroduction has done wonders for the ecology of the park and surrounding areas in what had become a pretty dire ecological predicament for a ton of species. Here is an article that kind of gets at the relationship (though in Oregon, not around the park) and to me draws a picture of an awesomely wild being that we do dishonor to by trying to contain https://www.outsideonline.com/2255971/very-old-man-wolf
It was good. Most of the AOC stuff was leaked out ahead so nothing big there. The last segment was great. Hopefully all of that shit can come to fruition. Although after Theranos, I get pretty skeptical of the 'too good to be true' stuff on 60 Minutes.
This lottery story is insane - we already had a thread https://www.the-mainboard.com/index...igan-man-cracks-lottery-code-wins-big.173026/
Last nights episode was just great My wife was crying hysterically during the WWII segment When they pulled out the Bible, all of the feels
The antibiotics story was really good tonight. They estimate 10 million people will die every year by 2050 secondary to “superbugs” resistant to all known antibiotics, more than die from cancer. Unfortunately people won’t care until it’s too late. I wish the story would have focused more on the doctors and patients. I’ll spend 10 min. explaining to a patient why an antibiotic won’t help their viral illness. After the discussion they’ll nod as if they understand and then they will say “are you going to give me an antibiotic”. Good luck explaining the old axiom “there is no cure for the common cold”. A patient pays $20-$100 to see you, they want to leave with a Rx in hand. The doctor’s day is made easier by just giving the antibiotic, the patient leaves happy, they get better after a day or two (just like they would have without the abx), and everyone comes out ahead, if not just for that short period of time at great sacrifice to our long term future.
Another interesting angle would have been the pharmaceutical companies. One such company that was working on new antibiotics declared bankruptcy recently. There’s just no money in it. Why spend billions developing a new antibiotic a patient may only take for 7 days when you can work on a cholesterol medication they will be on for life. It is rare for new abx to come to market as a result. Pretty scary.
Well that was a terrifying episode. All 3 stories scared the shit out of me, most of all that FTD disease but also including that "music".
Had no idea he was 70 damn years old. I watched Pulp Fiction today by chance and really enjoyed him talking about how the famous lines he has in that one are his favorites of his career
Same. Really want ro invest in the tech, but there aren't any public opportunities..... Which means the idea is way too young RN.