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Discussion in 'The Mainboard' started by TrustyPatches, Mar 15, 2020.
especially as we've been hearing that the FDA OK'd some not so great antibody tests
and i think SF continues to do really well. huge difference between Northern Cali and Southern Cali in terms of behavior is my understanding
There are a lot of uneducated dipshits in SoCal.
Baffling how well some SE Asian countries handled this. Truly remarkable how government policies and citizen response make a difference.
Also responsible media.
Caution with this data. While true, we don't know if it means lack of protection. 100% of these people still had T-cell responses which may provide significant protection
Was coming to post this.
Along these lines, have you read this? https://www.researchsquare.com/article/rs-35331/v1
It claims that they have identified people who while without infection showed T Cell responses due to prior infections of an unrelated common cold coronaviruses... I am curious if this is even possible.
I had not seem this work. Implications for vaccine development - it suggests that you'd want to develop vaccines that produce diverse T-cell responses across various epitopes.
To your other question, yes, heterologous cross-immunity is a well described thing.
Your mind has a lot of control over your body. Ask anyone who has had anxiety/panic attacks. It's really hard but try to stay positive. I got my fingers crossed that your test comes back negative. Hang in there my man.
This is one theory why kids are being less affected - they frequently get coronaviruses and might have some innate cross immunity
truth. I’m in socal and people don’t give a shit. I think we’ll fall back in line though. Sister in heart of SF and they have been pretty obedient and consistent from the beginning.
This is 100%. Lots of REDS in SoCal that DNGAF about masks or “being told what to do”. I’d be willing to bet 75% of Karen mask videos are filmed in SoCal.
I’m in East SF Bay burbs and it’s 100% masks everywhere indoors. I haven’t braved the dining scene outside of takeout at this point, nor do I intend to for foreseeable future, so can’t comment there.
IIRC the bay area counties went under actual "shelter in place" orders before anybody had done anything outside of like Seattle and NYC. They were aggressive early. And to further the point, many locales now being effected never went so far as to issue *that* type of order.
Multisystem inflammatory syndrome in children: Two U.S. studies in the New England Journal of Medicine offer insight into multisystem inflammatory syndrome in children (MIS-C). In a CDC analysis of nearly 190 children and adolescents with MIS-C in 26 states, nearly three quarters had been healthy previously. Most patients had at least four organ systems involved. Some 8% had coronary artery aneurysms. In a separate study of 100 affected children in New York State, 97% had tachycardia. In both studies, roughly 80% of patients needed intensive care, and the mortality rate was 2%. An editorialist notes that compared with patients with Kawasaki disease, those with MIS-C "are older and have more intense inflammation and greater myocardial injury."
Classroom exposure: A small study in Emerging Infectious Diseasesprovides some evidence that infected teachers could pass SARS-CoV-2 to their students in a traditional classroom setting. A symptomatic teacher returned to the classroom in late February after a trip to Europe. The teacher tested positive for SARS-CoV-2 on March 1. Among five students who attended interactive classes in which the teacher walked around the room, two had serology results suggestive of SARS-CoV-2 infection. None of the 16 students in noninteractive classes — in which the teacher mostly stayed in one place — tested positive for antibodies. The authors conclude: "Widespread school closures have mostly eliminated the risk for classroom transmission of SARS-CoV-2. However, these results suggest that classroom interaction between an infected teacher and students might result in virus transmission."
Bay Area SIP started March 17 at 12:01a and was originally scheduled to conclude 11:59p on April 7. Seems like eons ago considering we’re now in way worse shape nationwide. Hopefully we’re out of this by March 17 2021.
So apparently one pandemic wasn’t enough
I’m going to pistol whip the next person...
Someone asked about an update on the various Vaccines in development.
It looks like they posted a new update.
Very informative thread. I really think we (Southern California) were doing well at first, then selfish humans did their thing and I think some local politicians and business owners bent to peer pressure and desire to make some cash. The percentage of positives still aren’t catastrophic, but are heading in the wrong direction and the sheer number of people can overwhelm the medical infrastructure.
Full article https://science.sciencemag.org/content/sci/368/6498/1422.full.pdf
Will be very interesting to see if the “deeper lung penetration” of the aerosols = more severe Covid is actually true. Sounds kinda bullshit but who really knows.
makes you feel some kinda way when you think about those pictures of crowded bars
LOL at “silently spreading”. Guess that makes C19 different than all other viruses.
also interesting how that article paints a picture of significant uncertainty with respect to aerosolized transmission outdoors... specifically the bits about the variables that might result in the particles lasting longer in the air, rather than the more common narrative of how breezes and such make the transmission highly unlikely. (And I get that viral load is thought to be low in most of these scenarios anyway, ftr)
I prefer my aerosols to be loud and rambunctious
Has anyone seen this yet?
I have seen some other studies showing cases identified prior to January 2020, in other areas and some of these are a bit confusing.
i can't believe those samples still existed lol
So the State Health Officer for Alabama said he won’t require masks here because it’s too difficult to enforce. We require seat belts but somehow that is not too difficult to enforce
Can the SHO require masks? Seems like that’s the Governor’s choice to make. Her job should be to forcefully advocate for masks and let her boss make the decision after listening to all sides.
He said it during the governors press conference today. She acknowledges that cases are getting out of control so her only action is for Alabama to continue doing what we are doing right now.
She is running some adds about wearing masks staring Bo Jackson and Charles Barkley. Guess she doesn’t want Bama to be represented in that campaign
Here’s the strategy: Auburn fans will listen to Bo and Charles.
Then get them to say they hope Alabama fans don’t wear them so they catch corona.
Bama fans wear masks to spite Aubren.
Boom, Alabama is saved.
Is there any way to find historical data on ICU bed capacity?
This site uses a scale, as opposed to a raw %, which isn't great
Click on the state and select 'Show' the metric you want
Has anyone heard any information about recovered patients getting re-infected?
What type of headaches are usually associated with Covid.
This seems relevant
There were early suggestions that reinfections might be happening when recovered patients got a + diagnostic test. Turned out to be inactive CV RNA. So those weren't reinfections. Not to say it hasn't happened.
I don't think anybody knows how well antibodies will combat future exposures or how long those antibodies will stay in our bodies.
That would be good news, of course it also seems to be making a huge assumption that these 20-30 year olds don’t pass it on to anyone in a higher risk category
Right. I just thought if it checks out it seems good that, at this time, the hospitals don't seem to be overrun given the spike in cases.
We posting covid truthers in here now?
That guy doesn’t work for hospitals. If I read between the lines, he owns a chain of urgent cares that have clearly had their revenue crushed by the shut downs. He has an agenda just like the folks he’s claiming you should not listen to. He also admits to absolutely horrible antibiotic stewardship and should be heavily investigated by payers if they are providing antibiotics so commonly like that to mild Covid cases. Regardless, it’s great if the death rate stays low in these states. Let’s not celebrate yet. Young people still die and younger people can get very sick. Those people give it to older people. The caution is warranted. The “fear” is not.
I’m skeptical it’s even real but the $$ motivation is there
I'm sure it's been addressed, but Docs are saying they're seeing a lot more severity in cases. In other words, younger people are now ending up in ICU. We know why more young people are becoming infected, but why the uptick in the strength of the virus?