COVID-19 info thread

Discussion in 'The Mainboard' started by TrustyPatches, Mar 15, 2020.

  1. THF

    THF BITE THE NUTS, THUMB IN THE ASS!
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    Guy on Reddit posted his experience with the Pfizer vaccine. Obviously he could have received the placebo but it’s doubtful from his reaction. I figured I would share.

    So I got Pfizer's Covid vaccine.

    Got the trial vaccine after volunteering for it: got two shots separated by three weeks period and it was ... interesting. Went to Baylor and nasal swab was done, they drew two vials of blood and shot me up with the vaccine. The first day after the first shot was not comfortable, shoulder was hurting, I had a fuzzy head, a mild headache and general fatigue. Headache went away the next day as did the fatigue but my shoulder still hurt the next day. Third day after the shot I was back to 100%.

    Second shot hit me harder, shoulder was hurting even more, I had chills but no fever and general fatigue lasted for a day.

    Then, I went to get a serological antibody test on my own, three weeks after the first shot and voila - they found a "ton" of Covid antibodies in my blood so I am pretty much close to being immune. I will keep masking up as I do not want to test the fate, lol.

    Also they mentioned the study will continue through 2022 to determine the length of immunity.
     
  2. Room 15

    Room 15 Mi equipo esta Los Tigres
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    Dude didn't get the placebo.
     
  3. pnk$krtcrÿnästÿ

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    thanks reddit guy. Way to follow protocol and shit all over data integrity
     
  4. pnk$krtcrÿnästÿ

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    Seriously. It's a double blind study and the fucker goes and gets an antibody test? That's so shitty. Fuck him.
     
  5. Lyrtch

    Lyrtch My second favorite meat is hamburger
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    need my reddit karma bro
     
  6. Uncle Tupelo

    Uncle Tupelo Well-Known Member
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    They literally tell you not to do that shit before you agree to participate.
     
  7. BWC

    BWC It was the BOAT times, it was the WOAT times
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    Fucking people
     
  8. pperc

    pperc Well-Known Member
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    this. fucking piece of shit.
     
  9. pperc

    pperc Well-Known Member
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    because it will change that persons behavior whether they know it or not.
     
  10. Uncle Tupelo

    Uncle Tupelo Well-Known Member
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    Exactly. It was mentioned like 3 seperate times in the information video during my first appt.
     
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  11. Room 15

    Room 15 Mi equipo esta Los Tigres
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    Oddly enough I don't think they told me not to do it.

    Luckily uncle pperc did
     
  12. pnk$krtcrÿnästÿ

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    and then blasts his shitty idea all over reddit. If there's any justice in this world, someone will dox his ass.
     
  13. pnk$krtcrÿnästÿ

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    why the fuck would you?
     
  14. pperc

    pperc Well-Known Member
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    Pfizer will find him
     
  15. HoosDaMan

    HoosDaMan Grumpy
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    And kill him
     
  16. pnk$krtcrÿnästÿ

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    and then no one will
     
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  17. infected donkey

    infected donkey Arkansas Razorbacks
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    So got a follow up that I have to submit a video talking about why I wanted to get into the trial to get into the system.
     
  18. bertwing

    bertwing check out the nametag grandma
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    Just send them this and say it’s you

     
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  19. Doc Louis

    Doc Louis Well-Known Member
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    And remove the chip implanted with the second shot.
     
  20. John McGuirk

    John McGuirk member of the blue tiger club
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    honestly the first shot sounds similar to my flu shot last week.
     
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  21. Pile Driving Miss Daisy

    Pile Driving Miss Daisy It angries up the blood
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    They mentioned it to me, but the informed consent packet definitely asks you to not get such a test. Regardless if both the Pfizer and Moderna second shots are eliciting such a strong reaction it's probably obvious to most that you actually got the vaccine.
     
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  22. Room 15

    Room 15 Mi equipo esta Los Tigres
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    you don’t understand the desire to know if you have immunity to a virus that’s killing people?
     
  23. BWC

    BWC It was the BOAT times, it was the WOAT times
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    Well, that's not how it works anyway, but ok.

    Fuck every last person who gets a trial vaccination with this mindset. They're hurting everybody and delaying our ability to get this under control. Selfish twats.
     
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  24. slogan119

    slogan119 Her?
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    Plus we don’t yet have a determination as to whether you can still infect others once innoculated, right?
     
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  25. Room 15

    Room 15 Mi equipo esta Los Tigres
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    Not sure why you assume everyone does it with selfish and antagonistic intent.

    What percentage of study enrollees know the first thing about study integrity, statistics, etc. not everyone thinks like a scientist.

    which is why the initial education is important.
     
  26. BWC

    BWC It was the BOAT times, it was the WOAT times
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    That's not at all what I said.

    Agreed 100% with the importance of informing and properly educating participants. It should be perfectly clear that you DO NOT do what was done to start this sidebar discussion.
     
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  27. Room 15

    Room 15 Mi equipo esta Los Tigres
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    I may have combined you and pnk$krtcrÿnästÿ 's comments, but the question was why would someone do that. To me, it's a very clear and logical desire for someone until they know better.
     
    #7277 Room 15, Sep 23, 2020
    Last edited: Sep 23, 2020
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  28. BWC

    BWC It was the BOAT times, it was the WOAT times
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    The question becomes is it ignorance or willful ignorance. If the latter, fuck those people. That's what I was getting at with the mindset. Apologies if I was unclear.
     
  29. tjsblue

    tjsblue I was right at the time
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    Guy is involved in “blind study” and goes to unblind himself. I know we are setting a pretty low bar for Americans right now because of reasons, but fuck the ignorance too. It’s Reddit so internet is going to internet and mr cool had to show how cool he is going going around the rules and being Superman of immunity, but like was already said by you and others fuck him. Ignorant or not IMO. Even if it wasn’t crystal clear. Thanks for listening.
     
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  30. RonBurgundy

    RonBurgundy Well-Known Member

    We are being told to expect a “small number” of vaccines by Nov 1. Probably in the 100s maybe 1000s. Pfizer and Moderna likely.

    our ID guys think it will be more likely Jan 1.
     
  31. xec

    xec Well-Known Member
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    It’s bullshit of course. Just before the election the White House will announce that a vaccine is being distributed. The Secretary of HHS will “approve” a small number of doses for distribution. Publicly he and the WH will greatly embellish the number being distributed. The distributed doses will somehow be encumbered with red tape so they are not actually administered. After the election they will be quietly recalled.
     
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  32. slogan119

    slogan119 Her?
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    And a few of those people will die and never be heard from again
     
  33. Henry Blake

    Henry Blake No Springsteen is leaving this house!

  34. pperc

    pperc Well-Known Member
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    This test isn’t that much more affordable (cost to run)
     
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  35. Henry Blake

    Henry Blake No Springsteen is leaving this house!

    ^Are there any new developments on rapid/home tests besides that story? I haven't really seen any..
     
  36. Redav

    Redav My favorite meat is hotdog
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    We're using them to play football
     
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  37. pperc

    pperc Well-Known Member
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    These aren’t rapid or home, just to be clear. The only benefit is they use saliva as the sample. Still require sensitive lab based PCR.
     
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  38. Tiger Tiger Woods Y'all

    Tiger Tiger Woods Y'all Putting big balls in little holes, circa 1995
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    My taste and smell come and go. Now like 6 weeks post exposure. Still have lingering nasal congestion.
     
  39. Uncle Tupelo

    Uncle Tupelo Well-Known Member
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    This might be a dumb question, but during my appointment for my second shot, I asked the doctor if the vaccine being widely available by mid 2021 was a reasonable goal. She acted like there was no way because the trial takes 2 years to fully complete to collect full double blinded efficacy data. There is no way that it takes 2 years for something like the Pfizer vaccine to become available to the public, correct? (Assuming there are no setbacks safety-wise).

    I figured if antibodies are present in our bloodwork, and there are no serious side-effects, the vaccine would start to be rolled out sometime in Spring of 2021. I figured safety would be the first priority, then efficacy, The downside of waiting 2 years for full results, even if we determine the vaccine is safe, seems incredibly high.
     
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  40. AlternativeFactsRule

    AlternativeFactsRule Mmm ... Coconuts
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    Production of antibodies is not the same thing as demonstrating efficacy. The downside of giving a bunch of people a vaccine that doesn’t actually provide protection is pretty great. It means lots of people out and about acting as if they are immune and can’t transmit the disease to others when they aren’t and they can. Also, it would pour gas on the anti-vaxx fire.
     
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  41. Uncle Tupelo

    Uncle Tupelo Well-Known Member
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    Yeah, that makes sense. Hearing 2 years before a vaccine was a pretty big downer, but I get it.
     
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  42. AlternativeFactsRule

    AlternativeFactsRule Mmm ... Coconuts
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    I think they’re going to be push to show some efficacy prior to that. I don’t think it will be that long. Unless the data doesn’t support its efficacy.
     
  43. pperc

    pperc Well-Known Member
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    Most doctors wouldn’t know the first thing of vaccine development (or clinical trial design generally). I wouldn’t expect this one to be any different but I could be wrong.
    While I haven’t done the math myself, no way any of these companies are using a small enough sample size to require 2 years to get the requisite number of events to readout efficacy. That said, lots of things we won’t know for a while like whether the vaccine halts transmission or just reduces morbidity.
    Also, thank you for participating!
     
  44. AlternativeFactsRule

    AlternativeFactsRule Mmm ... Coconuts
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    Just to clarify - efficacy at say 6 months and 2-5 years could be different for a vaccine. If a given sars-cov-2 vaccine shows significant efficacy at 6 months, I think you can make a valid public health argument in favor of widespread distribution of that vaccine even if you suspected efficacy would plummet at the 2 year mark. We’ve shown that we aren’t willing to test, contact trace, and isolate to control the virus so a short term patch vaccine could basically do the same thing those measures would have.
     
  45. pperc

    pperc Well-Known Member
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    100%
     
  46. indeed

    indeed All In The Game
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    Thread. Grab a drink, it will take a awhile.

     
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  47. pnk$krtcrÿnästÿ

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    That was excellent, thanks
     
  48. Room 15

    Room 15 Mi equipo esta Los Tigres
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    Bookmarking for next shit
     
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  49. Henry Blake

    Henry Blake No Springsteen is leaving this house!

    NEJM article arguing for rapid tests to receive much more emphasis.
    https://www.nejm.org/doi/full/10.1056/NEJMp2025631?query=featured_home
    High-Frequency Testing with Low Analytic Sensitivity versus Low-Frequency Testing with High Analytic Sensitivity.

    A person’s infection trajectory (blue line) is shown in the context of two surveillance regimens (circles) with different analytic sensitivity. The low-analytic-sensitivity assay is administered frequently and the high-analytic-sensitivity assay infrequently. Both testing regimens detect the infection (orange circles), but only the high-frequency test detects it during the transmission window (shading), in spite of its lower analytic sensitivity, which makes it a more effective filter. The window during which polymerase chain reaction (PCR) detects infections before infectivity (green) is short, whereas the corresponding postinfectious but PCR-detectable window (purple) is long.

    [​IMG]
     
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