COVID-19 info thread

Discussion in 'The Mainboard' started by TrustyPatches, Mar 15, 2020.

  1. Uncle Tupelo

    Uncle Tupelo Well-Known Member
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    Not a doctor, but the docs where I got it told me Tylenol was fine to take after, but to avoid ibuprofen for 72 hours. Not sure why, but I listen to the experts.
     
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  2. RavenNole

    RavenNole Well-Known Member
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    im on a ton of different medications and supplements so I wasn’t sure if there were any meds specifically that could mess with it. My doctors haven’t said anything but not sure they would know. I will bring my full medication list to the appointment tomorrow and ask the pharmacist to be sure but it doesn’t seem like there are any that anyone is talking about from what I’ve seen. Figured I would ask.
     
  3. RonBurgundy

    RonBurgundy Well-Known Member

    There’s no data on many medications or supplements, and even the nsaid discussion is questionable, and not backed by robust evidence.

    In terms of other stuff, you’ll never see much for evidence because it doesn’t exist.
     
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  4. Russellin4885

    Russellin4885 Well-Known Member
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    I took Ibuprofen the day after my shot...oops
     
  5. Sportfan

    Sportfan From Six to Dumptime

    yes, I donated my dumbasses antibody rich plasma last month and recent vaccination was a disqualifier not just for Covid plasma but for other donations iirc. I’d check with them first.
     
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  6. RavenNole

    RavenNole Well-Known Member
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    RIP
     
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  7. Illinihockey

    Illinihockey Well-Known Member
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    thank you
     
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  8. Room 15

    Room 15 Mi equipo esta Los Tigres
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    Yea Red Cross told me not to come back for a year, but that was when I was in the trial before it was approved. I should follow up with them.
     
  9. xec

    xec Well-Known Member
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    I would go with pperc ’s recommendation on this, but a caveat. One of my son’s (age 27) had Covid and then got his Pfizer vaccine about 2 weeks later from the test. No problems for him, but as we all are aware, with Covid there’s not much certainty on these things.
     
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  10. Sportfan

    Sportfan From Six to Dumptime

    Just got a text from Dallas health department with a link to schedule my vaccine appointment. Only thing available is tomorrow. Cant do it then so hopefully this link keeps active and if it’s just one day out I’ll get it Friday afternoon.
     
  11. Sportfan

    Sportfan From Six to Dumptime

    Update: registered for tomorrow morning!
     
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  12. Hawks11

    Hawks11 The arsonist has oddly shaped feet
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    Just got the first vaccine (Pfizer) shot today!
     
  13. Pile Driving Miss Daisy

    Pile Driving Miss Daisy It angries up the blood
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    My fucking veins have been bruising badly with how many small blood samples we've had to give for the trial plus going for an annual physical. The last couple of times I've been stuck I've had a bad bruise show up on my inner arm, like I'm a junkie. I have no desire to not get anymore blood draws until after this trial is over.
     
  14. Room 15

    Room 15 Mi equipo esta Los Tigres
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    I have all star veins. Phlebotomists love me.
     
  15. Pile Driving Miss Daisy

    Pile Driving Miss Daisy It angries up the blood
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    I actually have very good veins as well so it's not an issue where they miss sticking me. I think they've just taken a beating the past several months, or maybe people are being too quick when they draw blood from me and that's causing the bruising.
     
  16. Room 15

    Room 15 Mi equipo esta Los Tigres
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    Idk sounds like you have quitter veins

    we’re in a damn pandemic they need to get it together
     
  17. goblue31602

    goblue31602 Well-Known Member
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    Phlebotomists hate me, the last time I gave blood i was told that the vein in my elbow was sideways, which is what made it difficult. Didn't know that was a thing, still not convinced it is, but giving blood samples has always been a challenge for me.
     
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  18. Henry Blake

    Henry Blake No Springsteen is leaving this house!
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  19. Illinihockey

    Illinihockey Well-Known Member
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    Can you mix and match booster shots? Like if you get pfizer and there’s a variant in the fall that you need a booster for, can you get moderna?
     
  20. Pile Driving Miss Daisy

    Pile Driving Miss Daisy It angries up the blood
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    Not yet, there's likely research going on but no way FDA approves that until probably fall boosters I bet.
     
  21. RonBurgundy

    RonBurgundy Well-Known Member

    Yeah I think there’s enough good data out there to stop giving Covid recovered people second shots. Unfortunately, I don’t think the cdc will Change policy. Also hard to police/know for sure.
     
  22. Room 15

    Room 15 Mi equipo esta Los Tigres
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    From an outsider who just reads bullshit on the internet, the slowness to adapt/change direction is what frustrates me most.

    I also realize that there’s reasonable scientific reasons for doing so.
     
  23. pnk$krtcrÿnästÿ

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    I'm getting a little tired of the "so and so is giving the vaccine to ineligible people!" headlines. It's like if a month after the Wright brothers took flight, people were already complaining about airline food
     
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  24. pperc

    pperc Well-Known Member
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    I think durability of protection without a second shot is an outstanding question, but nothing stops that second shot booster down the line. Worth the risk, IMO, of just switching to single dose. Honestly, I was thinking about this deeply today, but if Moderna and Pfizer had more time to do a more traditional clinical trial dvelopment path, they likely would've tested both a 1 shot and 2 shot regimen in Phase 2, and perhaps both in an outcomes study in Phase 3 and deemed the 1 shot sufficient for approval. Much cheaper on their COGS to do it as 1 shot and more administratively feasible from a clinical practice perspective. We have a 2 shot approval because they moved very fast and didn't want to miss.
     
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  25. Room 15

    Room 15 Mi equipo esta Los Tigres
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    If we are living in a simulation, I hope there’s another one that is giving the vaccine to whoever is available at the moment. And I hope they’re crushing it.
     
  26. Room 15

    Room 15 Mi equipo esta Los Tigres
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    Yea people worry about safety concerns of moving quickly, but I think you’re right that the biggest concern is missing out on the most effective solution possible in exchange for the fastest solution.
     
    #9026 Room 15, Mar 7, 2021
    Last edited: Mar 7, 2021
  27. pperc

    pperc Well-Known Member
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    100%. Well said, in a much pithier way than I did.
     
  28. Room 15

    Room 15 Mi equipo esta Los Tigres
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    Hopefully it’s still a priority to do that work. Could help in developing nations that will lag behind in vaccination.
     
  29. xec

    xec Well-Known Member
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    I had not considered CRISPR to be used this way, but I’m obviously naive. This is from Politico.com.

    https://www.politico.com/news/magaz...os-under-heaven-wuhan-lab-book-excerpt-474322

    “A little-noticed study was released in early July 2020 by a group of Chinese researchers in Beijing, including several affiliated with the Academy of Military Medical Science. These scientists said that they had created a new model for studying SARS-CoV-2 by creating mice with humanlike lung characteristics by using the CRISPR gene-editing technology to give the mice lung cells with the human ACE2 receptor — the cell receptor that allowed coronaviruses to so easily infect human lungs.

    After consultations with experts, some U.S. officials came to believe that this Beijing lab was likely conducting coronavirus experiments on mice fitted with ACE2 receptors well before the coronavirus outbreak—research that they hadn’t disclosed and continued not to admit to.”
     
    #9029 xec, Mar 8, 2021
    Last edited: Mar 8, 2021
  30. pperc

    pperc Well-Known Member
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    CRISPR engineering of mice is common practice. In this case, they likely were looking to create an animal model to study infections. How they did it isn’t the issue. The issue is did they have the required safety protocols and training to be doing it properly. I have, personally, no issue with this kind of work and the US does it all the time at USAMRIID.
     
  31. Room 15

    Room 15 Mi equipo esta Los Tigres
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    the upcoming debates about the morality of CRISPR will be fascinating
     
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  32. pperc

    pperc Well-Known Member
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    They’ve been happening for the last several years. There is nothing amoral about the technology itself. I agree that germ line engineering is a bad idea but for use in somatic cells is life changing for someone with an inherited or spontaneous disease.
     
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  33. IV

    IV Freedom is the right of all sentient beings
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    almost like there’s a reason everyone should get one
     
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  34. slogan119

    slogan119 Her?
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    A study released showed 78% of Covid-related hospitalizations were obese people.

    Yet another reason to lose some weight.
     
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  35. goblue31602

    goblue31602 Well-Known Member
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    Lost 60lb in the first half of 2020 :smug:
     
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  36. IV

    IV Freedom is the right of all sentient beings
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    I lost inches not weight
     
  37. goblue31602

    goblue31602 Well-Known Member
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    Went from a 38 waist to a 32. The new wardrobe wasn't cheap but definitely worth it.
     
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  38. IV

    IV Freedom is the right of all sentient beings
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    thats what I’m talking bout
     
  39. BWC

    BWC It was the BOAT times, it was the WOAT times
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    They've already been happening, essentially from Day 1 of the two CRISPR groups reporting their breakthroughs with the technology.
     
  40. Room 15

    Room 15 Mi equipo esta Los Tigres
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    I meant more when gen pop becomes more aware. I know the scientists are trying to come up with some guidelines
     
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  41. BWC

    BWC It was the BOAT times, it was the WOAT times
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    Gonna have lots of the classical failures of scientists sufficiently communicating with the public, I'm afraid. Will be anti-vaxxers on steroids. People tend to not trust what they don't or can't understand, sometimes for good, more often for bad.
     
    Room 15 likes this.
  42. DeToxRox

    DeToxRox Big Ten Westsideeeeeee
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  43. The Banks

    The Banks TMB's Alaskan
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    Move over Taiwan, there’s a new #1 in town.
     
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  44. RonBurgundy

    RonBurgundy Well-Known Member

    more evidence to support 1 dose in Covid + patients
     
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  45. Sportfan

    Sportfan From Six to Dumptime

    I’m thinking since I’m immunocompromised the second shot would still possibly be of benefit even though I had Covid in December. Is that logic acceptable in your opinion?
     
  46. Tommy Jefferson

    Tommy Jefferson Well-Known Member
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    Yep. It sure won’t hurt and if there is any doubt in your mind regarding your ability to mount a strong response, I’d take them both.
     
  47. Pasta88

    Pasta88 Canes, Bruins, Raps, Jays and Sunderland.
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    What’s the rationale for this decision when a. the vaccine has been previously tested and approved and b. there isn’t a proven link between the deaths and the vaccine? I obviously get why you’d want to look into it, but suspending them seems very conservative?
     
  48. VaxRule

    VaxRule Mmm ... Coconuts
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    Just as a general rule, governments approve a drug on a comparatively small population size. When those drugs get rolled out to the wider population, surveillance continues and bad outcomes that may have been missed by the small experiment size can be found. It’s on the government to review those results and protect the public.
     
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  49. Pasta88

    Pasta88 Canes, Bruins, Raps, Jays and Sunderland.
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    Yeah I understand that but it’s a bit frustrating since it’ll lead to some delay + it surely doesn’t help against vaccine reluctance. But hopefully it’ll be resolved quickly with a good outcome.

    At least the J&J vaccine was approved in Europe today too so it’s not all bad news.
     
  50. VaxRule

    VaxRule Mmm ... Coconuts
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    I know nothing about Denmark’s approval and review processes but I imagine it will be pretty quickly resolved.