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Discussion in 'The Mainboard' started by TrustyPatches, Mar 15, 2020.
he wont but the world would be a dramatically better place if he died
Bottom paged. Also I had no idea he was on this many meds daily. I feel like a shitty son not knowing he was taking this many.
Pravastatin sodium 40 MG high cholesterol¿Lisinopril 10 MG high blood pressure¿Levothyroxine 175 mcg. Low thyroid hypothyroidism ¿Tamsulosin hcl .4 MG¿Xarelto 20mg blood thinner afib ¿Tadalafil 20mg (I think this one is only when he goes to the dentist or something)
They have historical data for each state. Not perfect but not bad
I really need a link for this because a lot of my friends that have been great so far are on the verge of saying fuck it.
Ohio has published information on the number of Covid deaths at Long Term Care facilities. Cross referencing those numbers with the total state numbers, we are seeing that 70% of the confirmed deaths from Covid in Ohio are at long term care facilities.
Of the 1,781 deaths, 1,247 were in long term care.
the site posted here is perfect, shows # of tests, + tests, hospitalizations, and deaths on one page
52 last Friday
This is not an uncommon list of drugs for a man in his 70s to be taking. Anytime he adds a new medication, he should remain in contact with the prescribing physician about any new symptoms.
You have to be careful when reading the # of tests category as it has now come out that some states are reporting both the NP swab coronavirus and blood draw antibody tests combined as one number for their total number of tests done. That really isn’t helpful for tracking the number of tests being done.
The CDC is doing the same thing, apparently....
i know i say this once a week
but between incompetence failures in data reporting, and states intentionally misreporting data, and federal attempts to hide data
its continuing to be really fucking annoying and disheartening
They are and were while he was still in the hospital. So the drs should be aware of everything he was taking before they put him on the pneumonia med. Hopefully its nothing major.
Fucking damn it. Not surprising, but fucking damn it none the less
Here is a decent look at the hospitalization rates in Florida. It appears they are reporting the numbers but only the new cases being admitted, not the total hospitalized daily counts.
there are lots of medications that cause cognitive decline. Lots. Lots and Lots. Ertapenem shouldn't that I know of, but I haven't prescribe it since residency. Also, after major infections, people can get delirium in the hospital and while they recover. Delirium is temporary bouts of significant altered mental status and decline.
Also tadalafil is for getting boners because your parents are still having sex fyi.
Well, his dad is at least.
Makes you wonder what's going on at that dentist office
Delirium sucks. Watched my mom have it while in the hospital on a couple of occasions. Not something you want to witness. Hope your pops gets back to his full self as best he can Jax.
Maybe this is a dumb question but can you have covid-19 antibodies without having had the virus? Or if you have them, then that would have meant you were asymptomatic if you were never sick? I guess what I’m asking is are some people just naturally immune to this?
The human immune system is weird. You may have been exposed to something and developed antibodies to a part of it that looks close enough to some part of sars-cov-2 that those antibodies effectively fight off the virus too. That’s a theoretical possibility. The chances of that being reality are pretty low, though. Those antibodies are also less likely to show up in any commercial antibody testing.
if you test positive on the best antibody tests we have, you had the virus whether you had symptoms or not.
novel coronavirus to humans. No one on the planet has natural immunity. Either you had it/exposed to it and made antibodies, or the test gave a false positive.
If you have antibodies and they are good for x amount of time. If you come into contact with someone a month later who has covid does that restart your antibody clock?
I do not know how antibodies work if you couldn't tell.
It’s a good question. Small boosts by chronic exposure can be good for reinvigorating immunity or it can be very bad if too chronic. This virus won’t fall into the “too chronic” scenario so likely interactions with Covid-19 will serve as small “booster shots” assuming the virus doesn’t genetically drift away from the predominant antigenic sites.
Thanks for the info. And way to go pops I guess lol
It's been a long time since I really studied this, but don't memory B-cells get expressed at higher levels if a specific antibody, from previous exposure, binds to an epitope? I guess that's what you're saying with the booster shot analogy.
I get what you mean about being too chronic, that is making you ill again if you don't have strong immunity.
Yes, boosting will lead to your memory B cells dividing and some of those effector B cells will go back to memory cells. It’s a bit more complicated with central vs effector memory as well. And much is still poorly understood regarding cell fate and memory cell survival over time.
From what we know from immune interaction with cancers, some chronic viral infections, and the lcmv mouse model is that chronic exposure to antigen can lead to exhaustion phenotypes for your T cells (including Th and Tfh cells) which can impact humoral immunity as well. It’s not about making you ill, just that chronic exposure to antigen can make your immune cells stop recognizing that antigen.
That I did not know. I'm assuming (biiiig assumption) that is a consequence of our specific immune system being tasked with trying to protect against virtually everything, it can't dedicate all it's resources on trying to provide immunity against one specific pathogen.
What's the upshot for this when it comes to Covid research? How does it get fixed?
Trying to explain the evolutionary pressure (the “why”) is outside my scope on this one. Hard enough to keep up with the molecule mechanisms.
Very difficult imo.
Don't let your antibodies come into contact with your bodies or else they'll annihilate each other
I'm guessing it's not really surprising considering everything?
I know you're not making any of this up, but man, the names of some of this stuff makes it sound like you are.
Sweden will likely dodge a Belgium outcome
but man they really shot themselves in the dick and didn't accomplish what they intended at all
They could have saved so many lives
That was from February. In South Korea.
how does that diminish the studies findings?
Because times have changed. People are
far more aware and careful now.
But the study “findings” were that people can give it to others and that process can continue. Not sure that is ground breaking news and it likely shouldn’t be alarming.
Who the fuck is this poster? I’m not sure if I’m getting sucked into a troll or not