id say its pretty much a wash, i think mannigham and collie are both bench material, hightower is a slight downgrade from best and fits is slightly better than nicks. Id say best mainly offers more upside than hightower and Fitz mor upside than nicks (qb situation, not their own play) so it dpeends on where you want to take the gamble.
I like Manningham more than Collie, but that's just personal preference. Collie has no Manning right now, will probably get concussed, and has to contend with Wayne, Garcon, and Dallas Clark. Manningham only has to deal with Nicks and Eli is healthy. I would say the others wash out, Fitz is a bit better than Nicks and Best is better than Hightower in a PPR.
I think Hakeem Nicks is the best player in this deal. I'm not super high on Fitz to Kolb connection... On the other hand, I think Manningham is much better than Collie especially with the Peyton Manning situation uncertain and I also would rather have Hightower over Best, even thought its a PPR league. Hightower is an underrated receiver out of the backfield and doesnt have much competition for receptions outside of Santana Moss.